Buyer guide
Custom peptide synthesis pricing factors
Prepare a B2B synthesis brief and compare two quoted totals per milligram of delivered material.
Quote inputs
Pricing follows the defined project.
Custom peptide synthesis pricing cannot be separated from the technical and delivery fields. A useful quote request states the sequence or reference, required scale, purity target, packing, documents and destination together. Review the custom synthesis brief, the SPPS and LPPS method brief and the B2B procurement path before requesting a written quote.
Review custom synthesis serviceSequence and complexity
Provide the sequence, catalog reference or target structure and note any unresolved technical fields.
Synthesis scale
Separate the requested synthesis scale, bulk amount and intended vial or kit format.
Purity and documents
State the written purity target and whether COA, HPLC or independent testing records are required.
Packing and destination
Include vial, bulk, kit or private-label packing, destination country, postal code and timing.
Quote calculation
Compare two synthesis quotes per mg.
Enter the delivered material mass and total from each written quote. Use the same currency and confirm a comparable specification and cost scope. This tool calculates quoted cost per mg of delivered material; it does not calculate net peptide content.
Example: equal totals can hide different unit costs.
This quantity example uses no product price or quotation. It shows why delivered mass must be aligned before comparing written totals.
| Example quote | Delivered material mass | Written total | Cost per mg relationship |
|---|---|---|---|
| A | 1 g = 1,000 mg | Same as B | Baseline |
| B | 500 mg | Same as A | Twice A |
At the same total, B supplies half the delivered mass and costs twice as much per mg. Enter actual written totals in the calculator to compare a real project. Delivered material mass may include counterions, water or other components; this calculation does not establish peptide content.
Check the specification and cost scopeQuote comparison
Compare custom synthesis quotes on the same basis.
A lower total is only comparable when both quotes cover the same material and delivery scope. Use one specification revision, then check these fields before comparing unit prices.
| Quote field | What to align | Why the comparison can change |
|---|---|---|
| Sequence and form | Use the same sequence or structure revision, termini, modifications and requested salt or counterion form. | A quotation for a different material definition is an alternative scope. Record that difference before comparing the price. |
| Scale and delivered quantity | State the delivered amount and unit separately from any requested synthesis scale. Identify whether the amount refers to delivered material or net peptide content. | A stated synthesis scale does not by itself state the delivered amount. Compare unit prices only after the quantity basis is clear. |
| Purity, identity and content | Align the HPLC purity target and method basis; list identity evidence and any content or assay requirement separately. | HPLC peak-area purity is not peptide content or amount per vial. A lower quote may cover different analytical files or acceptance criteria. |
| Packing and aliquots | Specify bulk or vial format, amount per vial, vial or aliquot count and any label requirements. Ask which packing charges are included. | The same total amount can be supplied in different formats. Compare material and packing charges on the same requested format. |
| Documents and independent testing | List supplied records, tests still to be arranged, sample source, laboratory and written criteria. Identify initial test and retest cost responsibilities. | A requested COA or test is not automatically included. Confirm project-specific availability and distinguish document review from a new independent test. |
| Logistics and commercial terms | Separate material, packing, testing and logistics fields. Align destination, freight, duties or import responsibility, preparation and transit assumptions, and quotation validity. | A material price excluding shipping and a delivered total cover different costs. Compare the agreed total scope and validity date together. |
Mark unresolved fields as to be confirmed. Send the same editable synthesis RFQ for quotation review, and use the COA and HPLC guide to keep analytical terms comparable. This comparison does not confirm feasibility, a fixed price or delivery eligibility.
Commercial review
A quote should show what the number covers.
Ask the written quote to identify the item, unit, quantity, packing, available documents, testing scope, route and commercial terms. Route and delivery estimates are confirmed by destination and project stage.
Testing scope
Independent testing, sample source, laboratory, method and acceptance criteria are agreed before payment when required.
Document scope
Third-party COA and HPLC availability is confirmed for the applicable item or batch on a project basis.
Route and timing
Shipping option, destination handling, estimated transit and responsibility are reviewed for the destination.
Repeat supply
Keep the prior quote or lot reference available when reviewing changes to scale, packing or documents.
Quantity planning
Keep vial quantity separate from custom scale.
Vial-format, custom synthesis and bulk material quantities are reviewed against the project brief and confirmed in the written quote.
Read the order quantity guideVial format
The listed catalog kit format contains 10 vials.
Bulk material
Quantity, unit, packing and documents are set by the bulk project.
Custom sequence
Sequence, scale and purity target determine the synthesis review.
Written terms
Final pricing and delivery details are confirmed in the written quote.
Pricing FAQ
Questions before requesting a synthesis quote.
How is custom peptide synthesis pricing reviewed?
Pricing is reviewed against sequence or reference, synthesis scale, purity target, packing, requested documents or testing, destination and project terms. A written quote is prepared after the scope is clear.
Is there a public fixed price list?
No. Custom synthesis is project-based because sequence, scale, purity, packing, documents and destination can change the quotation scope.
How is the custom synthesis quantity confirmed?
Custom synthesis and bulk quantities are confirmed by project, based on the requested amount, sequence and specification.
Can I request pricing and documents together?
Yes. Send the sequence or reference, quantity, purity target, packing, destination and COA or HPLC requirements in one brief.
Next step
Compare written quote scope.
Send the sequence, scale, purity target, pack format, analytical requirements and destination for pricing review.